POSITIVE
mild to extreme mood lift, euphoria
increased willingness to communicate
increase in energy (stimulation)
ego softening
decreased fear, anxiety, and insecurities
feelings of comfort, belonging, and closeness to others
feelings of love and empathy
forgiveness of self and others
a sense of inner peace and acceptance of self, others, and the world
increased awareness & appreciation of music
increased awareness of senses (eating, drinking, smell)
increased tactile sensation (pleasure from the sense of touch and being touched)
life-changing spiritual experiences
sensations bright and intense
urge to hug and kiss people
analgesia, anti-nocioception, decreased pain perception
NEUTRAL
decreased appetite
visual distortion
rapid, involuntary eye jiggling (nystagmus)
mild visual hallucinations (uncommon)
moderately increased heart rate and blood pressure (increases with dose)
restlessness, nervousness, shivering
change in body temperature regulation
upwellings of unexpected emotion, emotional lability
strong desire to do or want more when coming down
NEGATIVE
(negative side effects increase with higher doses and frequent use)
inappropriate and/or unintended emotional bonding
anxiety or paranoia (less common than opposite)
agitation (less common than opposite)
tendency to say things you might feel uncomfortable about later
mild to extreme jaw clenching (trisma), tongue and cheek chewing, and teeth grinding (bruxia)
difficulty concentrating & problems with activities requiring linear focus
short-term memory scramble or loss & confusion
muscle tension
insomnia, inability to fall asleep when physically tired
erectile disfunction and difficulty reaching orgasm
increase in body temperature, hyperthermia, dehydration (drink water)
hyponatremia (don't drink too much water)
nausea and vomiting
headaches, dizziness, loss of balance, and vertigo
sadness on coming down, sense of loss or immediate nostalgia
post-trip Crash - unpleasantly harsh comedown from the peak effect
hangover the next day, lasting days to weeks
mild depression and fatigue for up to a week
severe depression and/or fatigue (uncommon)
possible strong urge to repeat the experience, though not physically addictive
possible psychological crisis requiring hospitalization (psychotic episodes, severe panic attacks, etc) (rare)
possible liver toxicity (rare)
possible neurotoxicity (controversial)
small risk of death; approximately 2 per 100,000 users have extreme negative reactions resulting in death (rare)
